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CONTRAVE Weight Loss

Have you been struggling with hunger pangs and cravings while trying to diet?

If you feel like your hunger is stopping you from losing weight, CONTRAVE® (naltrexone HCl/bupropion HCl) may be the right prescription solution for you.

CONTRAVE is an FDA-approved weight-loss medication containing a proprietary combination of naltrexone HCl and bupropion HCl. This weight loss drug is designed to curb hunger and cravings so that you can lose weight and keep that weight off.

If you think that CONTRAVE weight loss pills may be right for you, schedule a no-obligation phone consultation with Diet Doc. We’ll connect you with one of our medical weight-loss doctors, who will ask you questions and review your medical history to determine what weight loss therapies and medications are best for you. If your doctor believes you should integrate CONTRAVE into your diet plan, he or she will write you a prescription, and you can order your first prescription fill right away.

Please see Important Safety Information and Full Prescribing Information, including boxed warning at


How Does CONTRAVE Work?

CONTRAVE's two active ingredients, naltrexone and bupropion, are believed to target two areas of the brain: the hypothalamus and the mesolimbic reward center. The hypothalamus regulates hunger while the mesolimbic reward system triggers a sense of pleasure during rewarding experiences such as eating. Your brain seeks to repeat rewarding experiences to trigger those feelings of pleasure, which can cause you to crave food even when you’re not hungry.


Bupropion stimulates the POMC neurons of the hypothalamus, which fire neurotransmitters to reduce feelings of hunger. Naltrexone helps to keep these neurons active so that you don’t feel hungry between meals. Naltrexone and bupropion also regulate neurotransmitters in the mesolimbic reward system that are associated with cravings.


The safety, tolerability, and effectiveness of the CONTRAVE diet pill have been well-studied. Across three long-term studies, participants who took CONTRAVE lost approximately two to three times more weight on average than participants who used diet and exercise alone.



CONTRAVE may be effective for weight loss on its own, or it may be used as part of a complete weight loss program, as determined by your doctor.

Why Order CONTRAVE Through Diet Doc?

Diet Doc makes it easy to access the prescription weight loss medications, such as CONTRAVE, that you need when diet and exercise just aren’t enough. When you call us for a consultation, you’ll speak with an experienced medical weight-loss doctor who will customize a weight loss program for you. We recognize that every patient is different, and our team will look for the lifestyle changes and prescription medications that are most effective for you.

If your doctor prescribes any medications as part of your diet plan, you won’t have to wait long to receive them. We can ship CONTRAVE diet pills and any other medications you need the same day as your consultation.

After shipping your medication, we’ll keep working with you to make sure your diet plan is successful. Our doctors, nutritionists, nurses, and coaches are available six days a week, and you can always contact us if you need advice or have any questions. Ongoing support is the key to meeting your weight loss goals: our programs have a 98% success rate with patients who keep all doctor and nutritional consultations.

You don’t have to keep struggling with weight loss and maintenance on your own. Fill out our short form below to learn more about our diet plans, CONTRAVE, and other weight loss options.

CONTRAVE® is a registered trademark of Orexigen Therapeutics, Inc. registered with the U.S. Patent and Trademark Office.


Join the 55,000 Diet Doc patients who met their weight loss goals by signing up for your CONTRAVE consultation today.

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